Knowledgebase Knowledgebase on the internet giving information about 1150 metabolic diseases and differential diagnoses. Ressources Data maintenance is carried out regularly on the basis of publications, congress reports and personal communication. NMR-Panel Internet accessible register where quantitative NMR data for confirmed diseases are available as PDF reports (work in progress). Expert-Panel This is a communication platform where unsolved cases are discussed in a multidisciplinary format. About Us 30 years ago, we first started developing a web based knowledgebase for diagnostic support of IEM. The original approach of this disease database was developing an expert system for diagnostic support of genetic metabolic disorders. Moreover, we investigated the possibility of a computer assisted interpretation of the NMR reports.