LACTOSE INTOLERANCE, ADULT TYPE

Question 1

What is  LACTOSE INTOLERANCE, ADULT TYPE?

Accepted Answer

autosomal dominant
Lactase non-persistence (adult-type hypolactasia) is present in more than half of the human population and is caused by the down-regulation of lactase enzyme activity during childhood [Järvelä I 2009]

Question 2

Gibt es eine deutsche Bezeichnung?

Accepted Answer

Laktose-Intoleranz, Erwachsenentyp

Question 3

What is the link to OMIM ?

Accepted Answer

OMIN 223100

Question 4

Which enzymes are involved?

Accepted Answer

DNA replication licensing factor MCM6

Disease	LACTOSE INTOLERANCE, ADULT TYPE
Synonym	HYPOLACTASIA, ADULT TYPE
OMIM	223100 OMIM = Online Mendelian Inheritance of Men
Protein (UniProt)	DNA replication licensing factor MCM6
Gene locus	2p12.3
ICD
Summary	autosomal dominant Lactase non-persistence (adult-type hypolactasia) is present in more than half of the human population and is caused by the down-regulation of lactase enzyme activity during childhood [Järvelä I 2009]
Laboratory findings	D-Lactose inc (urine)
Symptoms	diarrhea flatulence onset, adolescent onset, childhood onset, infancy pain, abdominal