Visit Metagene.de!
Summary
INFECTIONS OF THE NEWBORN (TORCH) DD
Incidence of fetal infections due to selected organisms (1 per 100 live births) : Cytomegalovirus: 5-25 Rubella: 4-30 Toxoplasma gondii: 0.5-1 Herpes simplex: rare Treponema pallidum: 0.1
symptoms
anemia
blindness, visual loss, visual impairment
cataract
chorioretinitis
corneal clouding
failure to thrive
glaucoma
growth retardation
heart involvement
hepatomegaly (large liver)
hernia
hydrocephalus
hydrops fetalis
jaundice
mental retardation
microcephaly (<2 SD for age)
motor retardation
myocarditis
petechiae
pneumonia
prematurity
retinitis pigmentosa
seizures
skeletal changes, skeletal abnormalities
skin rash, eczematous or seborrhoic
splenomegaly (large spleen)
thrombopenia, thrombocytopenia
laboratory finding
CT, brain, abnormalities -
Literature
Millaire Aet al.Refsums disease. Apropos of 2 cases disclosed by myocardiopathy.Ann Cardiol Angeiol390173-1781990
Haas DKelley RI, Hoffmann GFInherited disorders of cholesterol biosynthesisNeuropediatrics320113-1222001
Frenkel Jet al.Increased urinary leukotriene E(4) during febrile attacks in the hyperimmunoglobulinaemia D and periodic fever syndromeArch Dis Child850185-1892001
Haas DKelley RI, Hoffmann GFInherited disorders of cholesterol biosynthesisNeuropediatrics320113-1222001