Visit Metagene.de!
Summary
ARTEFACTS-PHARMACEUTICAL PRODUCTS, INTERFERENCE IN AMINOACID AND ORGANIC ACID ANALYSIS: PARACETAMOL (ACETAMINOPHEN) DD
PITFALLS IN AMINOACID AND ORGANIC ACID ANALYSIS
Pitfalls in aminoacid and organic acid analysis and skin
biopsy due to metabolites of dietary origin, medications and additives:

PARACETAMOL (ACETAMINOPHEN), reversible inhibition of glutathione synthetase, inhibition of glutathione synthetase (GS) by
N-acetyl-p-benzoquinone imine (NAPQI)?
symptoms
metabolic acidosis
laboratory finding
5-Oxoproline0.000.00 increasedurineall
Literature
Boeckx RLHicks JMMethylmalonic acidemia with the unusual complication of severe hyperglycemiaClin Chem2881801-18031982
Lerner-Ellis JPet al.Mutation and biochemical analysis of patients belonging to the cblB complementation class of vitamin B(12)-dependent methylmalonic aciduriaMol Genet Metab002006
Sakazume Yet al.A case of middle-aged onset sialidosis type IRinsho Shinkeigaku448541-5442004
Dobson CMet al.Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduriaHum Mol Genet11263361-33192002
Ciani Fet al.Lethal late onset cblB methylmalonic aciduriaCrit Care Med2862119-21212000