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Summary
ANTICONVULSANT HYPERSENSITIVITY SYNDROME : CARBAMAZEPINE
Anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal multiorgan drug reaction that presents
with various cutaneous eruptions. There is a genetic predisposition to such reactions [Brown SC 2017].
symptoms
erythema multiforme
fever
liver involvement (acute, chronic, hepatitis)
skin rushes
laboratory finding
Transaminases increasedserum
Literature
Wang Let al.Long-term outcome and neuroradiological findings of 31 patients with 6-pyruvoyltetrahydropterin synthase deficiencyJ Inher Met Dis290127-1342006
Burlina ABet al.An unusual clinical and biochemical presentation of ornithine transcarbamylase deficiency in a male patientJ Inher Met Dis290179-1812006
Conter Cet al.Genetic heterogeneity of the GLDC gene in 28 unrelated patients with glycine encephalopathyJ Inher Met Dis290135-1422006